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Structure of 66572-56-3
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2-Bromoisonicotinic acid is a bench-stable, moisture-tolerant heterocyclic building block featuring a bromine atom at the 2-position of the pyridine ring. This strategic substitution enables direct coupling in cross-coupling reactions and facilitates downstream functionalization in medicinal chemistry and materials synthesis.
2-Bromoisonicotinic acid serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the pyridine ring’s C2 position. Its bromo group facilitates palladium-catalyzed cross-coupling reactions, including Suzuki and Stille couplings, while the carboxylic acid moiety allows for derivatization via amide or ester formation. The compound exhibits good bench stability and is compatible with standard purification methods, making it a practical choice for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: