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Structure of 66637-86-3
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3-Phenoxymandelic acid features a phenoxymethyl side chain attached to a mandelic acid core, combining a labile hydroxyl group with an aromatic ether functionality. This structure enables integration into bioactive scaffolds and facilitates downstream derivatization under mild conditions. The compound exhibits enhanced solubility in organic solvents compared to analogs, supporting its use in synthetic medicinal chemistry workflows.
3-Phenoxymandelic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its phenoxymethyl functionality offers enhanced metabolic stability and modulates lipophilicity, while the carboxylic acid group facilitates straightforward derivatization via esterification, amidation, or coupling reactions. The molecule exhibits good bench stability and is compatible with standard purification techniques, making it a practical choice for iterative synthetic campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: