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Structure of 66826-78-6
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5-Bromo-2,3-dihydrobenzofuran is a bench-stable heterocyclic scaffold featuring a bromine substituent at the 5-position and a saturated furan ring. This configuration enables direct functionalization in cross-coupling reactions and provides enhanced solubility over aromatic analogs. The compound serves as a key building block in medicinal chemistry and materials science.
5-Bromo-2,3-dihydrobenzofuran serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable aryl bromide functionality. The dihydrobenzofuran core provides structural rigidity and metabolic stability, while the bromine substituent offers high reactivity in Suzuki, Stille, and Negishi couplings. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: