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Structure of 66909-30-6
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2-Chloro-5-methylnicotinic acid is a bench-stable, electron-deficient heterocyclic carboxylic acid featuring a chloro group at the 2-position and a methyl substituent at the 5-position. This structural motif enables direct integration into pharmaceutical intermediates, particularly in kinase inhibitor scaffolds and bioactive heterocycles requiring enhanced lipophilicity and metabolic stability.
2-Chloro-5-methylnicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-chloro and meta-methyl substituents provide defined electronic and steric profiles, enhancing reactivity in coupling reactions and facilitating functional group transformations. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: