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CS-W001157 4
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(2S,4S,5R)-1-Benzyl-2-((R)-hydroxy(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium chloride

  • CAS No. 67174-25-8

  • Cat. No. CS-W011581
  • Molecule weight451.00
  • Purity≥95%
  • MDL No.MFCD00198105

*For research and further manufacturing use only, not for direct human use.

(2S,4S,5R)-1-Benzyl-2-((R)-hydroxy(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium chloride|CS-W011581

Structure of 67174-25-8

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General Information

  • CAS No. 67174-25-8
  • Cat. No. CS-W011581
  • Purity ≥95%
  • MDL No. MFCD00198105
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₇H₃₁ClN₂O₂
  • Molecular Weight 451.00
  • Synonym(s) None
  • SMILES O[C@H](C1=CC=NC2=C1C=C(OC)C=C2)[C@@]3([H])[N@@+](C[C@@H]4C=C)(CC5=CC=CC=C5)CC[C@H]4C3.[Cl-]

Description

N-Benzylquininium chloride (or Quibec) belongs to the class of cinchona family of alkaloids. It is used as a catalyst in the presence of hydroxide bases in various phase transfer reactions, epoxidations, alkylations, and Michael reactions.N-Benzylquininium chloride can be used as a phase transfer catalyst:In the sulfenylation of various -keto sulfoxides. To synthesize N-carbamoyl-protected -nitroamines from -amido sulfones by asymmetric aza-Henry reaction.

Synthesis

  • Route1
    • null|null
      100-44-7
    • In-stock
      Quinine|CS-8209
      130-95-0
    • ~70%
    • In-stock
      (2S,4S,5R)-1-Benzyl-2-((R)-hydroxy(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium chloride|CS-W011581
      67174-25-8

    References

    • Harigaya; Yamaguchi; Onda Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 5 p. 1321 - 1327

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   42.35
  • LogP   1.8922
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   6

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