2-Hydroxy-5-methoxybenzaldehyde

Name: 2-Hydroxy-5-methoxybenzaldehyde
Brand: ChemScene
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CAS No. 672-13-9
Cat. No. CS-W001206
Purity≥97%
MDL No.MFCD00003332

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FedEx Limited Quantities Ground	$0.00
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2-Hydroxy-5-methoxybenzaldehyde|CS-W001206

Structure of 672-13-9

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Description

2-Hydroxy-5-methoxybenzaldehyde has acaricidal activity against Tyrophagus putrescentiae.2-Hydroxy-5-methoxybenzaldehyde was used to synthesize radiolabeling precursor desmethyl-PBR06. It was used to study electroantennogram response of the vine weevil (Otiorhynchus sulcatus F.) to a broad range of volatile plant compounds. It was used in the synthesis of tetradentate Schiff base compounds.

Application

2-Hydroxy-5-methoxybenzaldehyde serves as a versatile building block in medicinal chemistry and natural product synthesis, enabling efficient access to bioactive heterocycles. Its ortho-hydroxyl and methoxy groups provide complementary sites for electrophilic substitution, oxidation, or coupling reactions. The aldehyde functionality facilitates reductive amination, Ullmann-type couplings, and condensation reactions with amines or hydrazines. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses of pharmaceutical intermediates and agrochemical scaffolds.

General Information

CAS No. 672-13-9
Cat. No. CS-W001206
Purity ≥97%
MDL No. MFCD00003332
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈O₃
Molecular Weight 152.15
Synonym(s) Salicylaldehyde, 5-methoxy-
SMILES COc1ccc(c(c1)C=O)O

Computational Chemistry Data

TPSA 46.53
LogP 1.2133
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Aldehyde

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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2-Hydroxy-5-methoxybenzaldehyde

CAS No. 672-13-9

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