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Structure of 676501-84-1
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This boronate ester features a bromothiophene moiety paired with a tetramethyl-substituted dioxaborolane ring, delivering high stability and compatibility in cross-coupling reactions. The electron-rich thiophene unit enhances reactivity in palladium-catalyzed transformations, enabling efficient coupling under standard conditions.
2-(5-Bromothiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boron building block for palladium-catalyzed cross-coupling reactions. The bromo-thiophene moiety enables efficient Suzuki-Miyaura coupling with diverse aryl and heteroaryl partners, facilitating the construction of biologically relevant thiophene-containing scaffolds. Its tetramethyl-substituted dioxaborolane ring ensures excellent shelf stability, minimal protodeboronation, and compatibility with common functional groups, making it ideal for modular synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: