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Structure of 677304-69-7
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1H-Indazole-7-carboxylic acid features a rigid, electron-deficient indazole core paired with a carboxylic acid group at the 7-position, enabling direct conjugation in bioactive molecule synthesis. This scaffold integrates readily into pharmaceutical intermediates and serves as a key building block for kinase inhibitors and fluorescent probes.
1H-Indazole-7-carboxylic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical scaffolds. Its carboxylic acid functionality enables direct amidation, esterification, and coupling reactions under standard conditions. The indazole core provides structural rigidity and hydrogen-bonding capacity, enhancing target affinity in medicinal chemistry applications. Bench-stable and readily purified by recrystallization, it functions effectively in multistep syntheses requiring functional group compatibility and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: