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Structure of 67768-61-0
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1-Cyclohexylimidazole is a bench-stable, moisture-tolerant imidazole derivative featuring a bulky cyclohexyl group that enhances solubility in organic media. This steric bulk reduces undesired nucleophilic side reactions while maintaining effective catalytic activity in amidation and esterification processes. The compound serves as a robust alternative to conventional imidazoles in synthetic workflows requiring enhanced stability and selectivity.
1-Cyclohexylimidazole serves as a robust, bench-stable nitrogen heterocycle widely employed in medicinal chemistry and catalysis. Its imidazole core provides strong hydrogen-bonding capacity and moderate basicity, enabling utility as a ligand in transition metal catalysis and a building block for bioactive scaffolds. The cyclohexyl substituent enhances lipophilicity and metabolic stability, facilitating incorporation into drug-like molecules. This compound reacts predictably with electrophiles and functions effectively in standard coupling and functionalization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: