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Structure of 67808-64-4
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Methyl 5-formylthiophene-2-carboxylate features a thiophene core bearing both aldehyde and ester functionalities, enabling direct incorporation into cross-coupling and condensation reactions. The electron-deficient ring facilitates nucleophilic addition, while the formyl group offers versatility in imine formation and conjugation. This bifunctional scaffold supports rapid access to complex heterocyclic architectures under standard conditions.
Methyl 5-formylthiophene-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted thiophenes and fused polycycles. The conjugated aldehyde and ester functionalities support diverse transformations including Wittig reactions, nucleophilic additions, and transition-metal-catalyzed couplings. Its bench-stable nature and compatibility with common protecting group strategies facilitate straightforward purification and integration into multi-step sequences for medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: