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CS-W001157 4
Total: USD 88.00

2-(azetidin-1-yl)ethanol

  • CAS No. 67896-18-8

  • Cat. No. CS-D0268
  • Purity≥98%
  • MDL No.MFCD09743797

*For research and further manufacturing use only, not for direct human use.

2-(azetidin-1-yl)ethanol|CS-D0268

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General Information

  • CAS No. 67896-18-8
  • Cat. No. CS-D0268
  • Purity ≥98%
  • MDL No. MFCD09743797
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO
  • Molecular Weight 101.15
  • Synonym(s) N-(2-Hydroxyethyl)azetidine
  • SMILES OCCN1CCC1

Description

2-(azetidin-1-yl)ethanol features a strained azetidine ring linked to an ethanediol chain, delivering enhanced nucleophilicity and solubility. This combination enables efficient incorporation into bioactive scaffolds and facilitates conjugation workflows under mild conditions.

Application

2-(Azetidin-1-yl)ethanol serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient incorporation of both amine and alcohol functionalities. Its azetidine ring imparts enhanced metabolic stability and improved binding affinity in bioactive molecules. The compound exhibits good bench stability, facilitates straightforward purification, and participates reliably in standard coupling and derivatization reactions, making it a practical choice for scaffold diversification and lead optimization workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   23.47
  • LogP   -0.3156
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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