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CS-W001157 4
Total: USD 88.00

Diethyl isopropylidenemalonate

  • CAS No. 6802-75-1

  • Cat. No. CS-0128347
  • Purity≥96%
  • MDL No.MFCD00009147
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Diethyl isopropylidenemalonate|CS-0128347

Structure of 6802-75-1

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Description

Diethyl isopropylidenemalonate serves as a versatile synthon in asymmetric synthesis, featuring a stabilized enol ether moiety that enables selective Michael additions and cycloadditions. The electron-deficient double bond facilitates conjugate functionalization, while the isopropylidene group provides steric protection and enhanced shelf stability under standard conditions.

Application

Diethyl isopropylidenemalonate serves as a versatile Michael acceptor and key building block in heterocyclic synthesis, enabling efficient access to substituted pyrrolidines and piperidines via cycloaddition or nucleophilic addition. Its stable enol ether functionality offers enhanced bench stability and compatibility with diverse reaction conditions, facilitating straightforward purification and scalability in medicinal chemistry workflows.

General Information

  • CAS No. 6802-75-1
  • Cat. No. CS-0128347
  • Purity ≥96%
  • MDL No. MFCD00009147
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₆O₄
  • Molecular Weight 200.23
  • Synonym(s) Isopropylidenemalonic Acid Diethyl Ester; Diethyl isopropylidenemalonate
  • SMILES O=C(OCC)/C(C(OCC)=O)=C(C)/C

Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.449
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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