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CS-W001157 4
Total: USD 88.00

Diethyl vinylphosphonate

  • CAS No. 682-30-4

  • Cat. No. CS-D0588
  • Molecule weight164.14
  • Purity≥98%
  • MDL No.MFCD00009079

*For research and further manufacturing use only, not for direct human use.

Diethyl vinylphosphonate|CS-D0588

Structure of 682-30-4

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General Information

  • CAS No. 682-30-4
  • Cat. No. CS-D0588
  • Purity ≥98%
  • MDL No. MFCD00009079
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃O₃P
  • Molecular Weight 164.14
  • Synonym(s) Vinylphosphonic Acid Diethyl Ester
  • SMILES CCOP(OCC)(C=C)=O

Description

Diethyl vinylphosphonate (DEVP) can be used as a precursor for the synthesis of: , -unsaturated phosphonates by reacting with arylboronic acids via Pd-catalyzed MizorokiHeck reaction.2-(arylamino)ethyl phosphonates by condensing with primary and secondary amines via the aza-Michael addition reaction.It can be also employed as a monomer unit for the preparation of high-molecular-weight polymer, poly(diethyl vinylphosphonate)using lanthanide complexes.{18)

Application

Diethyl vinylphosphonate serves as a versatile synthon in C–C bond formation, enabling efficient access to α,β-unsaturated phosphonates via Michael addition and conjugate functionalization. Its vinyl group exhibits high reactivity toward nucleophiles and transition-metal-catalyzed coupling processes, while the phosphonate moiety provides excellent stability and ease of purification. The compound functions reliably in multistep sequences, facilitating the construction of bioactive heterocyclic scaffolds and pharmaceutical intermediates under standard laboratory conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 3278
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   2.396
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   5

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