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Structure of 685517-67-3
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2,6-Difluoro-3-iodopyridine offers a strategically fluorinated pyridine scaffold with enhanced electrophilicity at the 3-position due to iodine substitution. This combination enables efficient cross-coupling reactions under mild conditions, particularly in palladium-catalyzed transformations. The molecule's bench-stable nature and compatibility with diverse reaction environments streamline synthetic workflows in medicinal chemistry and materials science.
2,6-Difluoro-3-iodopyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient access to substituted pyridines via palladium-catalyzed reactions. The ortho-fluoro substituents enhance reactivity in nucleophilic aromatic substitution, while the iodine moiety provides a reliable handle for Suzuki, Stille, and Negishi couplings. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: