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Structure of 686747-51-3
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Methyl 5-nitro-1H-indole-3-carboxylate features a nitro-substituted indole core with a methyl ester at the 3-position, offering enhanced solubility and reactivity in synthetic transformations. The electron-deficient aromatic system facilitates electrophilic substitution and coupling reactions, while the bench-stable ester group enables straightforward derivatization under standard conditions.
Methyl 5-nitro-1H-indole-3-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the C5 position via electrophilic substitution or transition-metal-catalyzed coupling. The nitro group enhances reactivity for subsequent reduction and derivatization, while the methyl ester provides a handle for selective hydrolysis or cross-coupling. Its bench-stable nature and compatibility with standard reaction conditions make it valuable for medicinal chemistry and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: