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CS-W001157 4
Total: USD 88.00

2-Bromo-6-(chloromethyl)naphthalene

  • CAS No. 689290-84-4

  • Cat. No. CS-0454946
  • Molecule weight255.54
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Bromo-6-(chloromethyl)naphthalene|CS-0454946

Structure of 689290-84-4

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General Information

  • CAS No. 689290-84-4
  • Cat. No. CS-0454946
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈BrCl
  • Molecular Weight 255.54
  • Synonym(s) None
  • SMILES C1=CC2=CC(=CC=C2C=C1CCl)Br

Synthesis

  • Route1

    References

    • Altenbach, Robert J.; Black, Lawrence A.; Chang, Sou-Jen; Cowart, Marlon D.; Faghih, Ramin; Gfesser, Gregory A.; Ku, Yi-yin; Liu, Huaqing; Lukin, Kirill A.; Nersesian, Diana L.; Pu, Yu-ming; Sharma, Padam N.; Bennani, Youssef L. Patent: US2004/92521 A1, 2004 ; Location in patent: Page/Page column 30 ; US 20040092521 A1
  • Route2
    • Methyl 6-bromo-2-naphthoate Adapalene Impurity|CS-0228706
      33626-98-1
    • ~%
    • 2-Bromo-6-(chloromethyl)naphthalene|CS-0454946
      689290-84-4

    References

    • Black, Lawrence A.; Nersesian, Diana L.; Sharma, Padam; Ku, Yi-Yin; Bennani, Youssef L.; Marsh, Kennan C.; Miller, Thomas R.; Esbenshade, Timothy A.; Hancock, Arthur A.; Cowart, Marlon Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 5 p. 1443 - 1446
  • Route3

    References

    • Ellingboe, John W.; Lombardo, Louis J.; Alessi, Thomas R.; Nguyen, Thomas T.; Guzzo, Frieda; et al. Journal of Medicinal Chemistry, 1993 , vol. 36, # 17 p. 2485 - 2493

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H312-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   4.3411
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

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