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CS-W001157 4
Total: USD 88.00

1-Methylpiperidine-4-carboxylic acid

  • CAS No. 68947-43-3

  • Cat. No. CS-W003320
  • Purity≥95%
  • MDL No.MFCD06659473

*For research and further manufacturing use only, not for direct human use.

1-Methylpiperidine-4-carboxylic acid|CS-W003320

Structure of 68947-43-3

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General Information

  • CAS No. 68947-43-3
  • Cat. No. CS-W003320
  • Purity ≥95%
  • MDL No. MFCD06659473
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃NO₂
  • Molecular Weight None
  • Synonym(s) N-Methyl-Piperidine-4-carboxylic acid
  • SMILES CN1CCC(CC1)C(=O)O

Description

1-Methylpiperidine-4-carboxylic acid features a sterically hindered piperidine core with a carboxylic acid group at the 4-position, enabling efficient incorporation into peptide-like scaffolds. The N-methyl substitution enhances metabolic stability and modulates solubility, while the acidic functionality facilitates conjugation and salt formation under standard conditions.

Application

1-Methylpiperidine-4-carboxylic acid serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles and peptidomimetics. Its well-defined stereochemistry and amide-forming capability facilitate efficient incorporation into lead compounds. The molecule exhibits favorable bench stability and compatibility with standard coupling protocols, supporting scalable synthesis and purification via common chromatographic methods.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P301+P310-P330-P501

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.4128
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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