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CS-W001157 4
Total: USD 88.00

Tubercidin

  • CAS No. 69-33-0

  • Cat. No. CS-5578
  • Molecule weightNone
  • Purity≥98%
  • MDL No.MFCD00056012

*For research and further manufacturing use only, not for direct human use.

Tubercidin|CS-5578

Structure of 69-33-0

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General Information

  • CAS No. 69-33-0
  • Cat. No. CS-5578
  • Purity ≥98%
  • MDL No. MFCD00056012
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄N₄O₄
  • Molecular Weight None
  • Synonym(s) 7-Deazaadenosine
  • SMILES O[C@H]1[C@@H](O)[C@H](N2C=CC3=C2N=CN=C3N)O[C@@H]1CO

Description

Intercalating into DNA duplexes and inhibiting RNA polymerase II, Tubercidin (CAS 69-33-0) induces transcriptional arrest in eukaryotic systems through irreversible incorporation into nascent RNA chains.

Application

Tubercidin (CAS 69-33-0) drives mechanistic studies of its own toxicity and resistance pathways in cellular systems. It acts as a potent selection agent. Researchers leverage this riboside analog to dissect RNAi silencing dynamics, probe transmethylation-dependent chemotaxis in eukaryotes, and uncover metabolic vulnerabilities in nucleotide metabolism.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅱ
Hazard Statements : H300
Precautionary Statements : P264-P270-P330-P405-P501

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Computational Chemistry Data

  • TPSA   126.65
  • LogP   -1.375
  • H_Acceptors   8
  • H_Donors   4
  • Rotatable_Bonds   2

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