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Structure of 691872-15-8
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5-Bromo-2-nitropyridin-3-ol features a bromine substituent at the 5-position and a nitro group at the 2-position on a pyridin-3-ol scaffold, delivering enhanced electrophilicity for cross-coupling reactions. The phenolic hydroxyl enables direct derivatization, while the electron-deficient ring facilitates nucleophilic substitution under mild conditions. This bench-stable, moisture-tolerant building block supports efficient synthesis of bioactive heterocycles in medicinal chemistry and materials science.
5-Bromo-2-nitropyridin-3-ol serves as a versatile building block for heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its bromine and nitro functionalities. The phenolic hydroxyl group provides additional site for derivatization, while the molecule exhibits sufficient bench stability for routine handling. Its orthogonal reactivity profile facilitates the construction of complex nitrogen-containing scaffolds relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: