8-Chloroimidazo[1,2-a]pyrazine

Name: 8-Chloroimidazo[1,2-a]pyrazine
Brand: ChemScene
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CAS No. 69214-33-1
Cat. No. CS-W004033
Purity≥98%
MDL No.MFCD09834910

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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8-Chloroimidazo[1,2-a]pyrazine|CS-W004033

Structure of 69214-33-1

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Description

8-Chloroimidazo[1,2-a]pyrazine is a heterocyclic compound featuring a chlorinated imidazo[1,2-a]pyrazine core, offering high stability and compatibility in synthetic transformations. This electron-deficient scaffold integrates readily into pharmaceutical intermediates, enabling efficient coupling reactions under mild conditions. Its bench-stable nature facilitates handling and storage without degradation.

Application

8-Chloroimidazo[1,2-a]pyrazine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to biologically active scaffolds. Its chloro substituent facilitates nucleophilic substitution and palladium-catalyzed coupling reactions, while the fused imidazopyrazine core offers enhanced metabolic stability and favorable binding interactions in target-directed synthesis. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for high-throughput screening campaigns and API development.

General Information

CAS No. 69214-33-1
Cat. No. CS-W004033
Purity ≥98%
MDL No. MFCD09834910
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₄ClN₃
Molecular Weight None
Synonym(s) None
SMILES ClC1=NC=CN2C=CN=C12

Computational Chemistry Data

TPSA 30.19
LogP 1.3827
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazine compounds

Key Words

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8-Chloroimidazo[1,2-a]pyrazine

CAS No. 69214-33-1

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