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Structure of 69321-60-4
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1,3-Dibromo-2-methylbenzene features a methyl-substituted benzene core with bromine atoms at the 1 and 3 positions, delivering enhanced electrophilic reactivity. This ortho-directing methyl group stabilizes reaction intermediates, enabling efficient coupling in palladium-catalyzed transformations. The molecule exhibits excellent bench stability and compatibility with diverse synthetic protocols.
1,3-Dibromo-2-methylbenzene serves as a valuable building block for the synthesis of substituted aromatic scaffolds. Its ortho-methyl group enhances regioselectivity in electrophilic substitution and facilitates downstream functionalization. The dibromo motif enables palladium-catalyzed cross-coupling reactions, including Suzuki-Miyaura and Stille couplings, under standard conditions. Bench-stable and readily purified by column chromatography, it functions reliably in multi-step syntheses of complex heterocycles and pharmaceutical intermediates.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: