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Structure of 6935-44-0
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Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate features a conjugated cyano-acrylate system paired with a phenolic hydroxyl group, enabling direct participation in Diels-Alder reactions and transition-metal-catalyzed couplings. This dual-functional scaffold integrates seamlessly into complex molecular architectures requiring precise electronic tuning and solubility control under standard conditions.
Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate serves as a versatile synthetic intermediate for constructing substituted chalcone analogs and heterocyclic scaffolds. Its conjugated enone–nitrile system enables efficient Michael additions, cyclizations, and palladium-catalyzed coupling reactions. The phenolic hydroxyl group provides a handle for derivatization or protection, while the ethyl ester facilitates subsequent transformations. Bench-stable and readily purified by recrystallization, it functions reliably in multistep synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: