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CS-W001157 4
Total: USD 88.00

5-Bromoisoindoline-1,3-dione

  • CAS No. 6941-75-9

  • Cat. No. CS-W004872
  • Purity≥98%
  • MDL No.MFCD00466049
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromoisoindoline-1,3-dione|CS-W004872

Structure of 6941-75-9

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Description

5-Bromoisoindoline-1,3-dione features a brominated isoindoline-1,3-dione core with enhanced electrophilicity at the C5 position, enabling efficient coupling in transition-metal-catalyzed reactions. The electron-deficient quinone moiety facilitates conjugation and stability under standard conditions, while the bromine substituent serves as a reliable handle for further functionalization via cross-coupling or nucleophilic substitution. This compound integrates seamlessly into complex molecular architectures requiring precise regiocontrol and reactive site availability.

Application

5-Bromoisoindoline-1,3-dione serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the C5 position via palladium-catalyzed cross-coupling reactions. Its stability under standard reaction conditions and compatibility with diverse functional groups make it well-suited for constructing complex heterocyclic scaffolds relevant to medicinal chemistry and materials science. The molecule functions as a robust dienophile in cycloadditions and provides a reliable platform for late-stage diversification in API development workflows.

General Information

  • CAS No. 6941-75-9
  • Cat. No. CS-W004872
  • Purity ≥98%
  • MDL No. MFCD00466049
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄BrNO₂
  • Molecular Weight 226.03
  • Synonym(s) 5-bromo-1H-isoindole-1,3(2H)-dione
  • SMILES O=C1NC(C2=C1C=CC(Br)=C2)=O

Computational Chemistry Data

  • TPSA   46.17
  • LogP   1.3327
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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