Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Hydroxy-4-methyl-2-nitrobenzoic acid

  • CAS No. 6946-15-2

  • Cat. No. CS-0100666
  • Purity≥98%
  • MDL No.MFCD00007106

*For research and further manufacturing use only, not for direct human use.

3-Hydroxy-4-methyl-2-nitrobenzoic acid|CS-0100666

Structure of 6946-15-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 6946-15-2
  • Cat. No. CS-0100666
  • Purity ≥98%
  • MDL No. MFCD00007106
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO₅
  • Molecular Weight 197.14
  • Synonym(s) copper 2,3,4,5,6,7-hexahydroxyheptanoate
  • SMILES O=C(O)C1=CC=C(C)C(O)=C1[N+]([O-])=O

Description

This hydroxy-methyl-nitrobenzoic acid features a strategically positioned para-nitro group and a vicinal hydroxyl moiety, enabling efficient coupling in synthetic routes. The carboxylic acid functionality facilitates derivatization, while the electron-withdrawing nitro group enhances reactivity in electrophilic substitution processes.

Application

3-Hydroxy-4-methyl-2-nitrobenzoic acid serves as a versatile building block for nitro-aromatic synthesis, enabling direct functionalization at the benzylic position and facilitating subsequent transformations such as reduction to amino derivatives or cyclization to heterocyclic scaffolds. Its ortho-hydroxyl and meta-methyl groups provide complementary reactivity for selective derivatization, while the carboxylic acid functionality supports straightforward coupling and salt formation. The compound exhibits sufficient bench stability for routine handling and purification via recrystallization or chromatography.

Synthesis

  • Route1
    • 3-Acetamido-4-methyl-2-nitrobenzoic acid|CS-0041647
      7356-52-7
    • ~96%
    • In-stock
      3-Hydroxy-4-methyl-2-nitrobenzoic acid|CS-0100666
      6946-15-2

    References

    • PFIZER PRODUCTS INC. Patent: WO2007/125405 A2, 2007 ; Location in patent: Page/Page column 27; 87 ; WO 2007/125405 A2
  • Route2
    • 3-Methoxy-4-methyl-2-nitrobenzoic acid|CS-0100667
      57281-77-3
    • ~%
    • In-stock
      3-Hydroxy-4-methyl-2-nitrobenzoic acid|CS-0100666
      6946-15-2

    References

    • Chemische Berichte, , vol. 91, p. 1242,1263 Journal of the Chemical Society, , p. 3646
  • Route3

    References

    • Journal of the Chemical Society, , p. 3646

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   100.67
  • LogP   1.30702
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Hydroxy-4-methyl-2-nitrobenzoic acid sigma3-Hydroxy-4-methyl-2-nitrobenzoic acid manufacturer3-Hydroxy-4-methyl-2-nitrobenzoic acid price3-Hydroxy-4-methyl-2-nitrobenzoic acid structure3-Hydroxy-4-methyl-2-nitrobenzoic acid SDSbuy 3-Hydroxy-4-methyl-2-nitrobenzoic acid3-Hydroxy-4-methyl-2-nitrobenzoic acid supplier3-Hydroxy-4-methyl-2-nitrobenzoic acid uses3-Hydroxy-4-methyl-2-nitrobenzoic acid molecular weightprice of 3-Hydroxy-4-methyl-2-nitrobenzoic acid3-Hydroxy-4-methyl-2-nitrobenzoic acid chemical name formula of 3-Hydroxy-4-methyl-2-nitrobenzoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label