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Structure of 6948-34-1
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6-Methylthiochroman-4-one features a fused chromanone core with a methylthio substituent at the 6-position, conferring enhanced lipophilicity and metabolic stability. This scaffold integrates readily into bioactive molecule libraries, offering favorable binding interactions in kinase inhibition and receptor modulation studies.
6-Methylthiochroman-4-one serves as a versatile heterocyclic building block for medicinal chemistry and natural product synthesis. Its thiochromanone core provides a rigid, planar scaffold with defined stereochemical control at C4, enabling selective functionalization. The methylthio substituent offers moderate stability and facilitates subsequent transformations such as oxidation to sulfoxide or sulfone, while the ketone functions as a key site for nucleophilic addition and enolate chemistry. This compound exhibits good bench stability and is amenable to standard purification methods, making it well-suited for iterative synthesis workflows in API development and lead optimization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: