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Structure of 6950-84-1
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1-(Naphthalen-1-yl)urea features a rigid aromatic urea scaffold that enhances π-stacking interactions and hydrogen bonding capacity. This structure supports robust binding in supramolecular systems and serves as a key intermediate in the synthesis of functionalized heterocycles and bioactive compounds.
1-(Naphthalen-1-yl)urea serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive urea derivatives through standard coupling protocols. Its naphthyl moiety imparts enhanced π-stacking and lipophilic character, while the urea group offers hydrogen-bonding capacity and metabolic stability. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns targeting kinase inhibitors and other target-directed scaffolds.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 1652
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Class : 6.1
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Packing Group : Ⅱ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P301+P310-P330-P405-P501
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Lot numbers can be found on the outside label of a product: