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Structure of 6959-47-3
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2-(Chloromethyl)pyridine hydrochloride was used as reagent in base catalyzed alkylation of p-tert-butylcalix[6]arene and p-tert-butylcalix[5]arene in DMF. It was used in the synthesis of Gd3+ diethylenetriaminepentaacetic acid bisamide complex, a Zn2+-sensitive magnetic resonance imaging contrast agent.
2-(Chloromethyl)pyridine (hydrochloride) serves as a versatile building block for pyridine-based heterocycles, enabling efficient alkylation and nucleophilic substitution reactions. Its chloromethyl group exhibits high reactivity under mild conditions, facilitating rapid functionalization while maintaining bench stability. The hydrochloride salt form enhances solubility and handling in aqueous or polar organic media, supporting broad compatibility in synthetic workflows including medicinal chemistry and catalyst development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P260-P270-P280-P280
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Lot numbers can be found on the outside label of a product: