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CS-W001157 4
Total: USD 88.00

NSC 100727

  • CAS No. 696-63-9

  • Cat. No. CS-D1129
  • Purity≥96%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

NSC 100727|CS-D1129

Structure of 696-63-9

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Description

4-Methoxybenzenethiol delivers a robust, moisture-tolerant thiol handle anchored to an electron-rich aromatic ring. This bench-stable derivative enables reliable conjugation in synthetic workflows, combining enhanced solubility with predictable reactivity for applications in bioconjugation and materials functionalization.

Application

4-Methoxybenzenethiol serves as a versatile building block in synthetic organic chemistry, enabling efficient access to thioether-functionalized aromatics and heterocyclic scaffolds. Its phenolic methoxy group enhances electron density at the aromatic ring, facilitating electrophilic substitution and improving solubility in polar solvents. The thiol functionality offers reliable coupling potential with alkyl halides, maleimides, and transition metal catalysts, supporting applications in ligand design, polymer chemistry, and peptide conjugation. Bench-stable and readily purified by distillation or recrystallization, it functions effectively in standard reaction conditions across industrial R&D workflows.

General Information

  • CAS No. 696-63-9
  • Cat. No. CS-D1129
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈OS
  • Molecular Weight 140.20
  • Synonym(s) Benzenethiol, p-methoxy- (6CI,7CI,8CI); 4-Mercaptoanisole; 4-Methoxythiophenol; 4-Methoxybenzenethiol
  • SMILES SC1=CC=C(OC)C=C1

Computational Chemistry Data

  • TPSA   9.23
  • LogP   1.9839
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: 3334
Class : 9
Packing Group :
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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