Lot numbers can be found on the outside label of a product:
1-O-Acetyl-2,3,5-Tri-O-benzoyl-beta-D-Ribofuranose
-
CAS No. 6974-32-9
- Cat. No. CS-W007928
- Purity≥98%
- MDL No.MFCD00005357
*For research and further manufacturing use only, not for direct human use.
Structure of 6974-32-9
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 6974-32-9
- Cat. No. CS-W007928
- Purity ≥98%
- MDL No. MFCD00005357
- Storage 4°C, sealed storage, away from moisture
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₂₈H₂₄O₉
- Molecular Weight 504.48
- Synonym(s) None
- SMILES O=C(C1=CC=CC=C1)O[C@H]2[C@H]([C@@H](O[C@@H]2COC(C3=CC=CC=C3)=O)OC(C)=O)OC(C4=CC=CC=C4)=O
Description
1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose serves as a key glycosyl donor in carbohydrate synthesis, featuring a protected ribose scaffold with orthogonal functional groups. The acetyl and benzoyl esters enable selective deprotection, while the β-configured anomeric center ensures stereospecific coupling. This derivative exhibits enhanced stability under standard conditions, facilitating reliable glycosylation reactions in complex oligosaccharide assembly.
Application
1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose serves as a versatile nucleoside precursor, enabling efficient glycosylation reactions in the synthesis of antiviral and anticancer ribonucleoside analogs. Its protected hydroxyl groups exhibit high regioselectivity and stability under standard coupling conditions, facilitating clean assembly of complex sugar moieties. The acetyl and benzoyl protections provide excellent functional group tolerance and simplify purification, making it well-suited for bench-scale synthesis and process development.
Synthesis
-
Route1
-
108-24-7 -
115459-50-2
- ~94%
-
In-stock
6974-32-9
References
-
Zhengzhou University; Analyse Testing And Research Center Of Henan Province Patent: EP2177527 A1, 2010 ; Location in patent: Page/Page column 11 ;
-
-
Route2
-
22224-38-0
-
108-24-7
- ~50%
-
In-stock
6974-32-9
References
-
Banda, Geetha; Srinivasulu; Ugandhar; Chakravarthy Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 8 p. 1920 - 1923
-
-
Route3
-
52783-53-6
-
108-24-7
- ~92%
-
In-stock
6974-32-9
References
-
Kim, Myong Jung; Jeong, Lak Shin; Kim, Joong Hyup; Shin, Ji Hye; Chung, Soon Yong; Lee, Sang Kook; Chun, Moon Woo Nucleosides, Nucleotides and Nucleic Acids, 2004 , vol. 23, # 4 p. 715 - 724
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 114.43
- LogP 3.5826
- H_Acceptors 9
- H_Donors 0
- Rotatable_Bonds 8
Similar Products
Other Classifications
- Chemical Biology Pharmaceutical Development and Drug Discovery Research Conjugation Chemistry/Click Chemistry Aldehyde Reactive Fluorophores and Labels
- Chemical Biology Pharmaceutical Development and Drug Discovery Research Nucleic Acid Chemistry Riboses, 2'-Deoxyriboses
- Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Nucleic Acid Chemistry Riboses, 2'-Deoxyriboses
- Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleobases and their Analogs
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 6974-32-9 sigma6974-32-9 manufacturer6974-32-9 price6974-32-9 structure6974-32-9 SDSbuy 6974-32-96974-32-9 supplier6974-32-9 uses6974-32-9 molecular weightprice of 6974-32-96974-32-9 chemical name formula of 6974-32-9