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Structure of 69872-17-9
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4-Bromo-6-azaindole is a heterocyclic building block featuring a bromine substituent at the 4-position and a nitrogen atom at the 6-position of the indole scaffold. This electron-deficient core enables direct functionalization in cross-coupling reactions, integrating seamlessly into pharmaceutical intermediates and advanced materials. The bromo group facilitates palladium-catalyzed transformations under standard conditions, while the azaindole framework enhances solubility and metabolic stability.
4-Bromo-6-azaindole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biaryl and heteroaryl scaffolds. The bromine substituent provides high reactivity in Suzuki, Stille, and Negishi couplings, while the 6-azaindole core offers enhanced solubility and hydrogen-bonding capacity. Its bench-stable nature and compatibility with diverse functional groups make it ideal for iterative synthesis in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: