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Structure of 699-91-2
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This 1-(2-hydroxy-3-methylphenyl)ethanone features a phenolic hydroxyl group flanked by a methyl substituent and a ketone functionality, enabling direct participation in metal coordination and hydrogen-bonding networks. The ortho-hydroxyketone motif supports intramolecular chelation, enhancing stability and reactivity in transition-metal-catalyzed transformations. Its bench-stable nature facilitates handling under standard conditions.
1-(2-Hydroxy-3-methylphenyl)ethanone serves as a versatile building block for synthesizing substituted benzofuran derivatives and bioactive heterocycles. Its ortho-hydroxy ketone functionality enables facile cyclization under acidic or oxidative conditions, while the methyl group provides a handle for further functionalization. The compound exhibits good bench stability and is readily purified by recrystallization, facilitating integration into multi-step synthetic sequences for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: