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CS-W001157 4
Total: USD 88.00

3-Methyl-2-(pyridin-3-yl)butanoic acid

  • CAS No. 699527-72-5

  • Cat. No. CS-0230658
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Methyl-2-(pyridin-3-yl)butanoic acid|CS-0230658

Structure of 699527-72-5

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General Information

  • CAS No. 699527-72-5
  • Cat. No. CS-0230658
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃NO₂
  • Molecular Weight 179.22
  • Synonym(s) None
  • SMILES CC(C)C(C1=CC=CN=C1)C(O)=O

Description

3-Methyl-2-(pyridin-3-yl)butanoic acid features a rigid pyridyl moiety linked to a branched aliphatic chain, delivering enhanced metabolic stability and improved membrane permeability. This structural motif enables efficient integration into bioactive scaffolds for medicinal chemistry applications, particularly in kinase inhibitor design and CNS-targeted drug discovery.

Application

3-Methyl-2-(pyridin-3-yl)butanoic acid serves as a versatile building block for bioactive heterocycles and pharmaceutical intermediates. Its structure combines a chiral α-branched carboxylic acid with a pyridine moiety, enabling facile derivatization via standard coupling reactions. The molecule exhibits good bench stability and functional group tolerance, facilitating its use in peptide conjugation, macrocyclization, and transition-metal-catalyzed transformations.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.9058
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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