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Structure of 701-16-6
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5-Fluoro-2-methylbenzo[d]oxazole features a fused bicyclic core with orthogonal electron-withdrawing fluorine and electron-donating methyl substituents, enabling tunable electronic properties. This structural motif enhances stability and facilitates incorporation into pharmaceutical scaffolds and functional materials.
5-Fluoro-2-methylbenzo[d]oxazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its ortho-fluorinated aryl ring facilitates directed metalation and electrophilic substitution, while the methyl group enhances metabolic stability. The fused oxazole core provides robustness under standard reaction conditions and supports functionalization via palladium-catalyzed cross-coupling. This compound functions effectively in the synthesis of kinase inhibitors and CNS-targeted molecules, offering high bench stability and ease of purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: