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Structure of 701-57-5
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4-Nitrothioanisole features a para-nitro group conjugated to a thioether linkage, delivering enhanced electron-withdrawing character and improved stability under standard conditions. This combination enables reliable participation in nucleophilic substitution and metal-catalyzed coupling reactions, particularly useful in the synthesis of functionalized aromatic sulfides.
4-Nitrothioanisole serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted thiophenes and sulfonamide derivatives. Its nitro group facilitates electrophilic substitution and subsequent reduction, while the thioether functionality offers orthogonal reactivity for selective transformations. Bench-stable and readily purified by recrystallization, it functions effectively in cross-coupling reactions and heterocycle synthesis under standard conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302+H312+H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: