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CS-W001157 4
Total: USD 88.00

2,7-Dichloro-9H-fluorene

  • CAS No. 7012-16-0

  • Cat. No. CS-W012896
  • Purity≥97%
  • MDL No.MFCD00032840

*For research and further manufacturing use only, not for direct human use.

2,7-Dichloro-9H-fluorene|CS-W012896

Structure of 7012-16-0

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General Information

  • CAS No. 7012-16-0
  • Cat. No. CS-W012896
  • Purity ≥97%
  • MDL No. MFCD00032840
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₈Cl₂
  • Molecular Weight 235.11
  • Synonym(s) 2,7-Dichlorofluorene; 2,7-Dichloro-9H-fluorene
  • SMILES ClC1=CC2=C(C=C1)C3=C(C=C(Cl)C=C3)C2

Description

2,7-Dichloro-9H-fluorene is a sterically constrained polycyclic aromatic compound featuring two chlorine substituents at the 2 and 7 positions of the fluorene core. This configuration imparts enhanced stability and electronic modulation, enabling its use in synthesizing functionalized fluorophores and conjugated materials. The dichloro substitution pattern facilitates selective coupling reactions under standard conditions, making it valuable for advanced organic synthesis applications.

Application

2,7-Dichloro-9H-fluorene serves as a versatile building block in the synthesis of fluorinated heterocycles and conjugated materials. Its dichloro substitution pattern enables selective palladium-catalyzed cross-coupling reactions, facilitating the construction of biaryl architectures with high regiocontrol. The fluorene core provides excellent thermal and oxidative stability, making it suitable for applications in organic electronics and medicinal chemistry scaffolds.

Synthesis

  • Route1

    References

    • Perumattam; Shao; Confer Synthesis, 1994 , # 11 p. 1181 - 1184
  • Route2
    • 2,7-Dichloro-9H-fluoren-9-one|CS-0548282
      6297-11-6
    • ~87%
    • In-stock
      2,7-Dichloro-9H-fluorene|CS-W012896
      7012-16-0

    References

    • Khurana, Jitender M.; Bansal, Geeti; Kukreja, Gagan; Pandey, Ravi R. Monatshefte fur Chemie, 2003 , vol. 134, # 10 p. 1365 - 1371
  • Route3
    • null|null
      106112-42-9
    • ~37%
    • In-stock
      2,7-Dichloro-9H-fluorene|CS-W012896
      7012-16-0

    References

    • Kajigaeshi, Shoji; Kadowaki, Toshiya; Nishida, Akiko; Fujisaki, Shizuo Bulletin of the Chemical Society of Japan, 1986 , vol. 59, p. 97 - 104

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   4.5646
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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