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Structure of 70201-42-2
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3,5-Dibromoisonicotinaldehyde features a pyridine core bearing two bromine substituents at the 3- and 5-positions and an aldehyde group at the 2-position. This electron-deficient scaffold enables direct incorporation into cross-coupling reactions and serves as a building block for functionalized heterocycles in medicinal chemistry and materials science.
3,5-Dibromoisonicotinaldehyde serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the 3- and 5-positions of the pyridine ring. Its aldehyde functionality facilitates nucleophilic additions, reductive aminations, and condensation reactions with amines or hydrazines under mild conditions. The ortho-bromine substituents provide complementary sites for palladium-catalyzed cross-coupling, supporting the construction of complex biaryl scaffolds. Bench-stable and readily purified by column chromatography, it functions efficiently in multi-step synthetic sequences requiring high regiocontrol and functional group compatibility.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H317-H319-H335
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Precautionary Statements : P280-P302+P352-P330
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Lot numbers can be found on the outside label of a product: