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CS-W001157 4
Total: USD 88.00

4-Hydroxy-2,6-dimethylbenzaldehyde

  • CAS No. 70547-87-4

  • Cat. No. CS-W005005
  • Purity≥97%
  • MDL No.MFCD00016979

*For research and further manufacturing use only, not for direct human use.

4-Hydroxy-2,6-dimethylbenzaldehyde|CS-W005005

Structure of 70547-87-4

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General Information

  • CAS No. 70547-87-4
  • Cat. No. CS-W005005
  • Purity ≥97%
  • MDL No. MFCD00016979
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₂
  • Molecular Weight 150.17
  • Synonym(s) 2,6-Dimethyl-4-hydroxybenzaldehyde
  • SMILES O=CC1=C(C)C=C(O)C=C1C

Application

4-Hydroxy-2,6-dimethylbenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted phenolic scaffolds. Its ortho-methyl groups enhance stability and direct electrophilic substitution, while the aldehyde functionality facilitates reductive amination, imine formation, and coupling reactions. Bench-stable and readily purified by recrystallization, it functions reliably in multistep sequences requiring functional group tolerance and predictable reactivity.

Synthesis

  • Route1
    • 4-((tert-Butyldimethylsilyl)oxy)-2,6-dimethylbenzaldehyde|CS-0891567
      378185-89-8
    • ~85%
    • In-stock
      4-Hydroxy-2,6-dimethylbenzaldehyde|CS-W005005
      70547-87-4

    References

    • Coppola, Gary M.; Gong, Yongjin Organic Preparations and Procedures International, 2007 , vol. 39, # 2 p. 199 - 202
  • Route2
    • null|null
      108-68-9
    • ~%
    • In-stock
      4-Hydroxy-2,6-dimethylbenzaldehyde|CS-W005005
      70547-87-4
    • In-stock
      2-Hydroxy-4,6-dimethylbenzaldehyde|CS-0254008
      1666-02-0

    References

    • Journal of the American Chemical Society, , vol. 68, p. 1862
  • Route3
    • null|null
      67-66-3
    • null|null
      108-68-9
    • ~10%
    • In-stock
      4-Hydroxy-2,6-dimethylbenzaldehyde|CS-W005005
      70547-87-4

    References

    • Yamada; Toyota; Takakura; Ishimaru; Sugawara New Journal of Chemistry, 2001 , vol. 25, # 5 p. 667 - 669

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.82154
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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