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CS-W001157 4
Total: USD 88.00

Sodium 2-(4-nitrophenyl)acetate

  • CAS No. 7063-24-3

  • Cat. No. CS-0157625
  • Purity≥95%
  • MDL No.MFCD00070537

*For research and further manufacturing use only, not for direct human use.

Sodium 2-(4-nitrophenyl)acetate|CS-0157625

Structure of 7063-24-3

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General Information

  • CAS No. 7063-24-3
  • Cat. No. CS-0157625
  • Purity ≥95%
  • MDL No. MFCD00070537
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆NNaO₄
  • Molecular Weight 203.13
  • Synonym(s) Sodium 4-Nitrophenylacetate
  • SMILES C1=C(C=CC(=C1)[N+](=O)[O-])CC(=O)[O-].[Na+]

Description

Sodium 2-(4-nitrophenyl)acetate is a bench-stable, moisture-tolerant reagent featuring a para-nitro group that enhances electrophilic reactivity. This anionic species integrates readily into synthetic pathways requiring electron-deficient aryl intermediates, enabling efficient coupling and functionalization under mild conditions.

Application

Sodium 2-(4-nitrophenyl)acetate serves as a versatile synthon in organic synthesis, enabling efficient construction of aryl-substituted acetic acid derivatives. Its bench-stable nature and high functional group tolerance facilitate straightforward transformations in multistep sequences. The compound functions effectively in nucleophilic acyl substitution and conjugate addition reactions, particularly valuable for accessing substituted benzene scaffolds relevant to pharmaceutical intermediates.

Synthesis

  • Route1
    • 4-Nitrobenzeneacetic acid Indobufen  Impurity|CS-0229459
      104-03-0
    • ~%
    • In-stock
      Sodium 2-(4-nitrophenyl)acetate|CS-0157625
      7063-24-3

    References

    • Polyhedron, , vol. 57, p. 83 - 93

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   83.27
  • LogP   -3.1088
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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