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Structure of 706786-42-7
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5-(Bromomethyl)-1,3-difluoro-2-methoxybenzene features a reactive bromomethyl group flanked by electron-withdrawing difluoro substituents and a methoxy handle, enabling selective functionalization in synthetic routes. The molecule combines enhanced stability with high electrophilicity, facilitating efficient coupling reactions under mild conditions. This aryl bromide serves as a valuable intermediate for constructing complex fluorinated scaffolds in medicinal chemistry and materials science.
5-(Bromomethyl)-1,3-difluoro-2-methoxybenzene serves as a versatile building block for the synthesis of fluorinated aromatic scaffolds. The bromomethyl group enables efficient Suzuki, Stille, and Ullmann coupling reactions, while the ortho-difluoro and methoxy substituents provide enhanced metabolic stability and modulated electronic properties. This compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: