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Structure of 706811-25-8
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5-(4-Bromophenyl)-6-hydroxypyrimidin-4(1H)-one features a brominated phenyl group attached to a pyrimidinone scaffold, enabling direct incorporation into heterocyclic architectures. The hydroxyl substituent enhances solubility and facilitates derivatization, while the electron-deficient ring system supports efficient coupling reactions under mild conditions. This compound serves as a key intermediate in medicinal chemistry for kinase inhibitor and antiviral agent development.
5-(4-Bromophenyl)-6-hydroxypyrimidin-4(1H)-one serves as a versatile building block for constructing biologically relevant pyrimidine scaffolds. The bromophenyl group enables palladium-catalyzed cross-coupling reactions, while the 6-hydroxy functionality offers opportunities for derivatization or tautomerization control. This compound exhibits good bench stability and facilitates efficient functional group interconversions in medicinal chemistry campaigns, making it a practical intermediate for targeted synthesis of heterocyclic compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: