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Methyl 2-oxo-1,2-dihydroquinoline-5-carboxylate

  • CAS No. 70758-34-8

  • Cat. No. CS-0006424
  • Purity95+%
  • MDL No.MFCD22665806

*For research and further manufacturing use only, not for direct human use.

Methyl 2-oxo-1,2-dihydroquinoline-5-carboxylate|CS-0006424

Structure of 70758-34-8

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General Information

  • CAS No. 70758-34-8
  • Cat. No. CS-0006424
  • Purity 95+%
  • MDL No. MFCD22665806
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₉NO₃
  • Molecular Weight 203.19
  • Synonym(s) 5-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester
  • SMILES COC(C1=C2C(NC(C=C2)=O)=CC=C1)=O

Synthesis

  • Route1
    • 2-Hydroxyquinoline-5-carboxylic acid|CS-0037441
      83734-43-4
    • ~%
    • Methyl 2-oxo-1,2-dihydroquinoline-5-carboxylate|CS-0006424
      70758-34-8

    References

    • Otsuka Pharmaceutical Co., Ltd. Patent: US4578381 A1, 1986 ;
  • Route2
    • null|null
      67-56-1
    • 2-Hydroxyquinoline-5-carboxylic acid|CS-0037441
      83734-43-4
    • ~84%
    • Methyl 2-oxo-1,2-dihydroquinoline-5-carboxylate|CS-0006424
      70758-34-8

    References

    • Uchida; Tabusa; Komatsu; Morita; Kanbe; Nakagawa Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3775 - 3786
  • Route3

    References

    • Saugues, Emmanuelle; Nauton, Lionel; Thery, Vincent; Anizon, Fabrice; Moreau, Pascale Bioorganic Chemistry, 2011 , vol. 39, # 4 p. 143 - 150

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.16
  • LogP   1.3147
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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