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CS-W001157 4
Total: USD 88.00

4'-Formyl-[1,1'-biphenyl]-4-carboxylicacid

  • CAS No. 70916-98-2

  • Cat. No. CS-0170951
  • Molecule weight226.23
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4'-Formyl-[1,1'-biphenyl]-4-carboxylicacid|CS-0170951

Structure of 70916-98-2

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General Information

  • CAS No. 70916-98-2
  • Cat. No. CS-0170951
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₀O₃
  • Molecular Weight 226.23
  • Synonym(s) 4'-FORMYL-BIPHENYL-4-CARBOXYLIC ACID
  • SMILES C1=C(C=CC(=C1)C2=CC=C(C=C2)C(=O)O)C=O

Description

4'-Formyl-[1,1'-biphenyl]-4-carboxylic acid features a dual functional group architecture: an aldehyde at the 4'-position and a carboxylic acid at the 4-position of the biphenyl core. This arrangement enables orthogonal reactivity, facilitating coupling reactions or conjugation strategies in synthetic organic chemistry and materials science applications. The molecule exhibits enhanced solubility in polar aprotic solvents and maintains stability under standard bench conditions.

Application

4'-Formyl-[1,1'-biphenyl]-4-carboxylic acid serves as a versatile bifunctional building block for the synthesis of biaryl scaffolds and functionalized heterocycles. Its orthogonal aldehyde and carboxylic acid groups enable sequential derivatization under standard conditions, facilitating coupling reactions, protection strategies, and conjugation workflows. The molecule exhibits good bench stability and is amenable to purification via recrystallization or chromatography, making it well-suited for use in medicinal chemistry campaigns and materials science applications requiring precise molecular architecture.

Synthesis

  • Route1
    • In-stock
      4-Formylphenylboronic acid|CS-W009126
      87199-17-5
    • null|null
      1005-30-7
    • ~10%
    • In-stock
      4'-Formyl-[1,1'-biphenyl]-4-carboxylicacid|CS-0170951
      70916-98-2

    References

    • Carlucci, Lucia; Ciani, Gianfranco; Maggini, Simona; Proserpio, Davide M.; Ragaini, Fabio; Gallo, Emma; Ranocchiari, Marco; Caselli, Alessandro Journal of Porphyrins and Phthalocyanines, 2010 , vol. 14, # 9 p. 804 - 814
  • Route2

    References

    • Journal of Porphyrins and Phthalocyanines, , vol. 14, # 9 p. 804 - 814
  • Route3
    • 4'-Formyl-biphenyl-4-carboxylic acid ethyl ester|CS-0340763
      70917-02-1
    • ~%
    • In-stock
      4'-Formyl-[1,1'-biphenyl]-4-carboxylicacid|CS-0170951
      70916-98-2

    References

    • Journal of the Chemical Society, , p. 100,101

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   54.37
  • LogP   2.8643
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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