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CS-W001157 4
Total: USD 88.00

(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(piperazin-1-yl)methanone Doxazosin Impurity

  • CAS No. 70918-00-2

  • Cat. No. CS-0228952
  • Molecule weight248.28
  • Purity≥98%
  • MDL No.MFCD01837119

*For research and further manufacturing use only, not for direct human use.

(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(piperazin-1-yl)methanone Doxazosin  Impurity|CS-0228952

Structure of 70918-00-2

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General Information

  • CAS No. 70918-00-2
  • Cat. No. CS-0228952
  • Purity ≥98%
  • MDL No. MFCD01837119
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₆N₂O₃
  • Molecular Weight 248.28
  • Synonym(s) N-[(1,4-Benzodioxane-2-yl)carbonyl]piperzine
  • SMILES O=C(C1COC2=C(O1)C=CC=C2)N1CCNCC1

Synthesis

  • Route1
    • null|null
      110-85-0
    • 2,3-Dihydrobenzo[b][1,4]dioxine-2-carboxylic acid Doxazosin  Impurity|CS-0228951
      3663-80-7
    • ~93%
    • (2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(piperazin-1-yl)methanone Doxazosin  Impurity|CS-0228952
      70918-00-2

    References

    • Bandgar; Bettigeri Synthetic Communications, 2004 , vol. 34, # 16 p. 2917 - 2924
  • Route2

    References

    • Chou, Wen-Chih; Tan, Chang-Wei; Chen, Shyh-Fong; Ku, Hao Journal of Organic Chemistry, 1998 , vol. 63, # 26 p. 10015 - 10017
  • Route3
    • null|null
      120-80-9
    • ~%
    • (2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(piperazin-1-yl)methanone Doxazosin  Impurity|CS-0228952
      70918-00-2

    References

    • Organic Preparations and Procedures International, , vol. 35, # 6 p. 603 - 608

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301+H311+H331-H373-H411
Precautionary Statements : P261-P273-P280

Quality Control

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Computational Chemistry Data

  • TPSA   50.8
  • LogP   0.2582
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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