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Structure of 714273-83-3
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4-(tert-Butyl)-1H-imidazole-5-carbaldehyde features a sterically hindered tert-butyl group that enhances stability and solubility in organic media. The aldehyde functionality enables direct coupling in multistep syntheses, while the imidazole core provides a robust scaffold for bioactive molecule design. This compound integrates seamlessly into pharmaceutical intermediates and functional materials.
4-(tert-Butyl)-1H-imidazole-5-carbaldehyde serves as a versatile building block in medicinal and process chemistry, enabling the synthesis of imidazole-based scaffolds through standard aldehyde transformations. Its tert-butyl group enhances steric stability and solubility, while the aldehyde functionality facilitates reductive amination, Grignard additions, and coupling reactions with broad functional group tolerance. The molecule exhibits excellent bench stability and ease of purification, making it well-suited for high-throughput screening and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: