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Structure of 71436-66-3
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1-Bromo-2-chloronaphthalene is a halogenated naphthalene derivative featuring bromine at the 1-position and chlorine at the 2-position. This configuration imparts enhanced reactivity in cross-coupling processes, particularly in palladium-catalyzed reactions. The compound exhibits good stability under standard conditions and serves as a valuable building block for synthesizing functionalized polycyclic architectures.
1-Bromo-2-chloronaphthalene serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling the construction of biaryl scaffolds under standard Suzuki, Stille, and Negishi conditions. The ortho-halogen substitution pattern provides predictable regioselectivity, while the molecule exhibits excellent bench stability and compatibility with diverse functional groups. Its defined reactivity profile makes it a reliable intermediate for synthetic sequences targeting complex heterocycles and pharmaceutical intermediates.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: