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Structure of 7149-59-9
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Diethyl 3-oxohexanedioate features a β-keto ester moiety flanked by two ester groups, enabling facile enolization and nucleophilic participation. This structural motif supports efficient carbon-carbon bond formation in Claisen condensations and Michael additions, making it a key building block for complex heterocycles and polyfunctional intermediates under standard conditions.
Diethyl 3-oxohexanedioate serves as a versatile synthon in carbonyl-based synthesis, enabling efficient construction of substituted cyclohexanones and heterocyclic scaffolds via Claisen condensation and related transformations. Its α,β-unsaturated ketone functionality supports robust Michael additions and aldol reactions, while the diester moiety facilitates sequential functionalization under mild conditions. Bench-stable and readily purified by distillation or chromatography, it functions reliably in multi-step sequences for natural product and pharmaceutical intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: