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Structure of 7149-65-7
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L-Pyroglutamic acid ethyl ester features a stable cyclic imide structure with a pendant ethyl ester group, enabling straightforward hydrolysis to the parent acid. This derivative enhances solubility and stability in organic solvents, facilitating its use in peptide synthesis and chemical biology applications.
L-Pyroglutamic acid ethyl ester serves as a versatile chiral building block for peptide and heterocyclic synthesis, offering bench-stable functionality with predictable reactivity in amide bond formation and cyclization protocols. Its protected γ-lactam core enables straightforward access to pyrrolidine-based scaffolds common in medicinal chemistry, with high compatibility in standard coupling reactions and ease of purification via flash chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: