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Structure of 717843-56-6
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3-Bromo-2-methoxy-5-methylpyridine features a pyridine core functionalized with bromo, methoxy, and methyl groups at strategic positions, enabling direct coupling in cross-coupling reactions. The electron-rich aromatic system enhances reactivity in palladium-catalyzed transformations, while the methoxy group improves solubility and stability under standard conditions. This scaffold serves as a key intermediate in medicinal chemistry and agrochemical synthesis.
3-Bromo-2-methoxy-5-methylpyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined regiochemistry and stability under standard reaction conditions. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the methoxy and methyl substituents provide orthogonal functional handles for further derivatization. Its bench-stable nature and predictable reactivity make it ideal for constructing complex heterocyclic scaffolds in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: