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CS-W001157 4
Total: USD 88.00

4'-Methyl-2,2':6',2''-terpyridine

  • CAS No. 72036-41-0

  • Cat. No. CS-0371253
  • Molecule weight247.30
  • Purity≥98%
  • MDL No.MFCD06796968

*For research and further manufacturing use only, not for direct human use.

4'-Methyl-2,2':6',2''-terpyridine|CS-0371253

Structure of 72036-41-0

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General Information

  • CAS No. 72036-41-0
  • Cat. No. CS-0371253
  • Purity ≥98%
  • MDL No. MFCD06796968
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₃N₃
  • Molecular Weight 247.30
  • Synonym(s) 4'-Methylterpyridine
  • SMILES N=1C=CC=CC1C=2N=C(C=C(C2)C)C=3N=CC=CC3

Description

4'-Methyl-2,2':6',2''-terpyridine features a methyl-substituted pyridine ring that enhances solubility and modulates electronic properties. This ligand integrates readily into coordination complexes, offering improved stability and tailored redox behavior in catalytic systems.

Application

4'-Methyl-2,2':6',2''-terpyridine serves as a versatile ligand in transition metal catalysis, enabling robust coordination to late-transition metals through its three nitrogen donor atoms. The methyl substituent enhances solubility and modulates electronic properties without compromising chelation efficiency. This compound facilitates catalytic cycles in cross-coupling and oxidation reactions, offering improved stability and ease of purification compared to unsubstituted analogs. Its predictable reactivity profile makes it a reliable choice for bench-scale synthesis and catalyst design.

Synthesis

  • Route1
    • null|null
      75-16-1
    • 4-(Methylsulfanyl)-6-(pyridin-2-yl)-2,2'-bipyridine|CS-0122197
      78570-35-1
    • ~80%
    • In-stock
      4'-Methyl-2,2':6',2''-terpyridine|CS-0371253
      72036-41-0

    References

    • Potts, Kevin T.; Usifer, Douglas A.; Guadalupe, Ana; Abruna, Hector D. Journal of the American Chemical Society, 1987 , vol. 109, # 13 p. 3961 - 3967
  • Route2
    • null|null
      594-27-4
    • [2,2':6',2''-Terpyridin]-4'-yl trifluoromethanesulfonate|CS-1179841
      134653-69-3
    • ~90%
    • In-stock
      4'-Methyl-2,2':6',2''-terpyridine|CS-0371253
      72036-41-0

    References

    • Odobel, Fabrice; Sauvage, Jean-Pierre; Harriman, Anthony Tetrahedron Letters, 1993 , vol. 34, # 50 p. 8113 - 8116
  • Route3
    • null|null
      207804-48-6
    • ~73%
    • In-stock
      4'-Methyl-2,2':6',2''-terpyridine|CS-0371253
      72036-41-0

    References

    • Armspach, Dominique; Constable, Edwin C.; Diederich, Francois; Housecroft, Catherine E.; Nierengarten, Jean-Francois Chemistry - A European Journal, 1998 , vol. 4, # 4 p. 723 - 733

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.67
  • LogP   3.51402
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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