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Structure of 7218-52-2
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4-Hydroxybut-2-ynoic acid features a conjugated alkyne-carboxylic acid motif paired with a terminal hydroxyl group, enabling direct incorporation into bioconjugation workflows. The electron-deficient alkyne facilitates efficient copper-catalyzed azide-alkyne cycloaddition, while the hydroxyl moiety offers a handle for derivatization or protection. This bifunctional scaffold supports modular synthesis in chemical biology and materials science applications.
4-Hydroxybut-2-ynoic acid serves as a versatile building block in synthetic organic chemistry, enabling access to functionalized γ-lactones and conjugated systems via cyclization or further derivatization. Its terminal alkyne and hydroxyl groups offer orthogonal reactivity for copper-catalyzed coupling and selective protection strategies. The compound demonstrates good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and natural product analog development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: